Research & Innovation in weight loss
Evidence-based care informed by research, clinical trials, and innovation
Dr Jess Mok believes that the best patient care is grounded in strong evidence, thoughtful innovation, and a deep understanding of the biology of disease.
Alongside her clinical practice as a Consultant Bariatric, Upper GI, and General Surgeon, she has an extensive background in research and clinical trials, particularly in the science of appetite regulation, weight loss, and metabolic health.
Why research matters to your care
Medical and surgical treatments evolve rapidly. Research ensures that care is:
Safe and evidence-based
Informed by the latest scientific understanding
Tailored to long-term outcomes, not short-term results
Grounded in realistic expectations
Dr Mok’s research background allows her to translate complex science into practical, patient-centred decisions.
Doctoral research in GLP-1 and weight loss
Dr Mok completed a PhD focused on the role of glucagon-like peptide-1 (GLP-1) in patients with suboptimal weight loss following bariatric surgery.
This work explored:
The hormonal drivers of appetite and satiety
Why some patients experience plateau or weight regain
The biological basis of variable responses to surgery and medication
This research underpins Dr Mok’s specialist interest in:
Weight-loss injections (GLP-1–based therapies)
Optimising outcomes after bariatric surgery
Supporting patients with weight regain or suboptimal results
Clinical trials and innovation
Dr Mok has been actively involved in national and international clinical trials investigating weight-loss medications and metabolic therapies.
Her work includes:
Recruitment into landmark GLP-1 clinical trials that informed the use of modern weight-loss injections in clinical practice
Research into medical therapies for patients with suboptimal weight loss
Ongoing interest in innovation to improve patient outcomes and experience
This experience provides first-hand insight into:
How new treatments work
Who benefits most
Limitations and side-effects
Real-world, long-term outcomes
Applying research to real-world patients
Dr Mok’s approach bridges the gap between research and everyday clinical care.
This means:
Avoiding “one-size-fits-all” treatment
Using medication thoughtfully rather than automatically
Recognising when surgery offers better outcomes
Supporting patients through plateaus, transitions, and maintenance
The goal is not simply weight loss, but sustainable health and quality of life.
Research-informed care beyond weight loss
Dr Mok’s research training also informs her wider practice, including:
Careful investigation of gastrointestinal symptoms
Thoughtful use of endoscopy and imaging
Integration of clinical nutrition into treatment planning
Avoidance of unnecessary procedures
This holistic approach is particularly important for patients with functional symptoms or complex presentations.
Innovation and future directions
Dr Mok has a strong interest in the future of weight management and metabolic care, including:
Digital health and patient-centred innovation
Supporting long-term behaviour change alongside medical treatment
Improving pathways for patients before and after bariatric surgery
Innovation is approached thoughtfully, with patient safety and evidence at its core.
Professional integrity and transparency
Research involvement does not mean experimental treatment in private practice.
All treatments offered by Dr Mok are:
Evidence-based
Clinically appropriate
Discussed transparently with patients
Aligned with current best practice
Book a consultation
If you would like expert advice informed by research and clinical experience, you are welcome to book a private consultation with Dr Jess Mok.